Renal
Renal disease (also known as kidney disease) represent a broad class of diseases caused by damages/abnormalities of the kidney, which can elicit many severe clinical symptoms. We offer disease models for Acute Kidney Injury (AKI), Chronic Kidney Disease (CKD) and Unilateral Ureteral Obstruction (UUO).
FEATURED DISEASE MODELS:
Acute Kidney Injury (AKI)
Rapid onset disease characterised by the loss of the kidney's excretory function and is typically diagnosed by the accumulation of end products of nitrogen metabolism (creatinine and urea) and/or decreased urine output. Currently, ARF models can be divided into ischemic-induced models, drug-induced models and sepsis-induced models, as well as others.
Chronic Kidney Disease (CKD)
Commonly considered as the progressive loss of kidney function, CRF can be induced by surgical procedures: freezing, electric coagulation, or infusions of drugs/substances, etc.
Ureteral Obstruction (UUO)
This is a standard model of renal fibrosis which is a major characteristic of prolonged renal disease. It is achieved through surgical ligation of either one or both ureters depending on the desired experimental requirement.
